Monika Kowalczyk, Danielle Dionne, Bo Li, Orr Ashenberg, Marcin Tabaka, Timothy Tickle, Karthik Shekhar, Michal Slyper, Julia Waldman, Jane Lee, Orit Rozenblatt-Rosen, Aviv Regev

For questions pertaining to the computation and analysis please contact: libo@broadinstitute.org

For question pertaining to the sample preparation and biological assay, please contact: monika@broadinstitute.org

Diverse cells of the immune system maintain and protect tissue function, integrity, and homeostasis upon changes in functional demands and diverse perturbations. Recent advances such as massively parallel single-cell RNA-sequencing and sophisticated computational methods help shed new light on this complexity. This immune cell census aims to profile up to 2M immunocytes, the first tranche of this is currently available. With computational methods optimized to a massive scale, we can readily identify cell types and markers, as well as the process of hematopoietic differentiation. The high quality and comprehensive reference map is provided as an open community resource for understanding human health and disease.

Currently, this study contains:

279,312 cells from bone marrow

254,941 cells from cord blood

340,972 cells from peripheral blood

Total 875,225 immune cells with 500 gene or more